AMRI’s expert chemists conduct lead optimization — the iterative process of inventing new chemical structures to identify an improved drug lead — with the goal of progressing your compound as a preclinical candidate. We also provide intellectual property support for proprietary compounds that advance to clinical testing.
Once our scientists identify a lead series, we synthesize new analogs, which typically requires multistep synthesis and high purity standards. Our world-class medicinal chemistry team, bringing decades of experience working with drug-like compounds, designs new compounds based on computational, structural and biological assay results.
We can also access specialized analytical and solid state services that provide the support to keep your compounds moving quickly through the discovery pipeline.
影音aV 影 先鋒A v電影 Access our lead optimization services individually or as an integrated package. Our complete suite of services includes:
- Computer-aided drug discovery (CADD)
- Structure-based drug design
- Medicinal chemistry
- Preparative chromatography, including supercritical fluid chromatography (SFC)
- In vitro DMPK and bioanalytical services
- Biological screening